179463-17-3

Caspofungin acetate is an antifungal medication that treats a variety of fungal infections. It is used to treat serious fungal infections, including candidemia (fungal infection in the blood), esophageal candidiasis (fungal infection of the esophagus), other candida infections, and aspergillosis (fungal infection in the lungs). Caspofungin acetate was approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) in 2001. Caspofungin acetate, also known as CANCIDAS, is synthesized from pneumocandin B0, a fermentation product of the fungus Glarea lozoyensis. The synthesis process involves chemical modifications at two sites of the peptide core, including: Reduction of a primary amide to an amine and Condensation of the hemiaminal moiety with ethylenediamine. Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. It is a good Chinese factory of Caspofungin acetate.

InChI:InChI=1/C52H88N10O15.2C2H4O2/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72;2*1-2(3)4/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75);2*1H3,(H,3,4)/t28?,29?,30-,33-,34-,35+,36-,37+,38-,40+,41+,42+,43?,44+,45+,46+;;/m1../s1