135575-42-7
- Product Name：Pneumocandin B0
- Molecular Formula：C50H80N8O17
- Purity：99%
- Molecular Weight：1065.21
Product Details:
CasNo： 135575-42-7
Molecular Formula： C50H80N8O17
Appearance： White to Off-White solid
Delivery Time： 2 weeks after order
Throughput： 100KG/Month
Purity： 99%
Synonyms: pneumocandin B(0); Caspofungin PneuMocandin B0 IMpurity; B0 PneuMocandin B0; pneumocandins Impurity; CFA/ CBR01; Pneumocandin B0 (L-688786); CS-492
Boiling point: 1442.9±65.0 °C
Density: 1.41±0.1 g/cm3
Solubility: DMSO (Slightly), Methanol (Sparingly)
Pka: 9.86±0.26
Flash point: 826.5±34.3 °C
Vapor pressure: 0.0±0.3 mmHg at 25°C
Refractive index: 1.630
Description:
Pneumocandin B0 is an antifungal lipopeptide that acts by inhibiting the synthesis of β-(1,3)-D-glucan, a component of fungal cell walls (IC50s = 70 and 67 ng/ml for inhibiting glucan synthase in C. albicans and A. fumigatus, respectively). It can be used to synthesize the echinocandin caspofungin acetate.
Uses:
Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, such as Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
Mechanism of action:
Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
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