1093861-60-9

  • Product Name:Afoxolaner
  • Molecular Formula:C26H17ClF9N3O3
  • Purity:99%
  • Molecular Weight:625.87
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Product Details:

CasNo: 1093861-60-9

Molecular Formula: C26H17ClF9N3O3

Purity: 99%

Synonyms: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 1-Naphthalenecarboxamide,4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-; afoxolaner-007; 4-(5-(3-Chloro-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide; Avrana; Afulana

Density: 1.53±0.1 g/cm3

Solubility: DMSO: ≥ 250 mg/mL (399.44 mM)

Form: crystalline solid

Color: White to off-white

Pka: 12.45±0.46

 

Description:

Afoxolaner is an insecticide and acaricide belonging to the isoxazoline family. Afoxolaner acts at ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes.

 

Uses:

Afoxolaner is used to treat and control flea and tick infestations in dogs.  After being ingested by a dog, afoxolaner is distributed throughout the dog's body.  When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.

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