What is the 4-Hydroxy-3-methoxybenzylamine hydrochloride?

4-Hydroxy-3-methoxybenzylamine hydrochloride is white to light yellow crystal powder, while it's Molecular Formula is C8H12ClNO2. white to light yellow crystal powder A metabolite of Capsaicin.

What is the CAS number for 4-Hydroxy-3-methoxybenzylamine hydrochloride?

The CAS number of 4-Hydroxy-3-methoxybenzylamine hydrochloride is 7149-10-2.

What is the 4-Hydroxy-3-methoxybenzylamine hydrochloride?

4-Hydroxy-3-methoxybenzylamine hydrochloride is white to light yellow crystal powder, while it's Molecular Formula is C8H12ClNO2. white to light yellow crystal powder A metabolite of Capsaicin.

What is the CAS number for 4-Hydroxy-3-methoxybenzylamine hydrochloride?

The CAS number of 4-Hydroxy-3-methoxybenzylamine hydrochloride is 7149-10-2.

Product Class

7149-10-2

Product Name：Vanillylamine Hcl
Molecular Formula：C₈H₁₂ClNO₂
Purity：99%
Molecular Weight：189.642

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Product Details:

CasNo： 7149-10-2

Molecular Formula： C₈H₁₂ClNO₂

Appearance： white to light yellow crystal powder

Chinese Factory Supply Best Quality Vanillylamine Hcl 7149-10-2 Best Price

Molecular Formula:C8H12ClNO2
Molecular Weight:189.642
Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:0.00102mmHg at 25°C
Melting Point:219-221 °C (dec.)(lit.)
Boiling Point:292.9 °C at 760 mmHg
Flash Point:130.9 °C
PSA：55.48000
LogP:2.36180

Vanillylamine Hcl(Cas 7149-10-2) Usage

Description

Vanillylamine Hydrochloride, also known as Vanillylamine HCl, is a chemical compound obtained as a metabolite of Capsaicin. It serves as a biochemical reagent and organic compound utilized in various research applications within the life sciences field.

Uses

Vanillylamine Hydrochloride serves as a valuable reagent in biochemical research, particularly in studies related to metabolism, cellular signaling, and pharmacology. Its inclusion in synthetic pathways enables the creation of novel substances with potential applications in pharmaceuticals, agrochemicals, and materials science. Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufacturing of Building Blocks, Reference Compounds & Impurities, Natural products, APIs & Intermediates, At present, Huarong Pharm has successfully delivered innovative R&D products and services to more than 3,000 partners across the world. Our goal is to become a world-class leading company to support life science innovation and manufacturing.

Preparation Method

Initial Reaction: 3-methoxy-4-hydroxybenzaldehyde oxime is added to a reaction container, along with alcohol and a composite catalyst. Hydrogen gas is introduced under normal pressure conditions to protect the reaction, followed by heating to facilitate the reaction process.

Filtration: After completion of the reaction, the mixture is filtered to remove any solid impurities or by-products, yielding a filtrate containing the desired compound.

Acidification: Hydrochloric acid with a mass percentage concentration of 30% is added to the filtrate to adjust its pH value to approximately 1. This step facilitates the precipitation of Vanillylamine Hydrochloride as a white crystal.

Drying: The precipitated Vanillylamine Hydrochloride crystals are filtered out and subjected to vacuum drying to remove any remaining moisture and solvents, resulting in the final product.

InChI:InChI=1/C8H11NO2/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,10H,5,9H2,1H3/p+1

7149-10-2 Relevant articles

Biocatalytic synthesis of palmitoyl vanillylamide in supercritical carbon dioxide through amidation of vanillylamine hydrochloride and palmitic anhydride by lipase

Kuan-Ju Liu a , Kuan-Miao Liu b , Hung-Min Chang c

, Food Chemistry Volume 102, Issue 4 , 2007, Pages 1020-1026

Among five lipases tested, immobilized Mucor miehei lipase, Lipozyme IM, was most effective in synthesizing this analog. The reaction conditions for analog synthesis were optimized and were 50 °C, 17 MPa and pH 8 for 23 h using vanillylamine hydrochloride and palmitic anhydride at a molar ratio of 5/15 as substrates catalyzed by Lipozyem IM at a concentration of 0.5% (w/w). The residual enzyme activity was about 40% and 15% after a 46- and 69-h repeated amidation reaction in a batch reaction under optimized conditions, suggesting further modification of conditions was required.

Synthesis and elucidation of deuterated vanillylamine hydrochloride and capsaicin

Sang Wook Kim, Jeong Hoon Park, Soon Jae Jung, Tae Bum Choi, Min Goo Hur, Seung Dae Yang, Kook Hyun Yu

Journal of Labelled Compounds and Radiopharmaceuticals, Volume52, Issue13 November 2009 Pages 563-565

Although the biosynthesis of capsaicin is known to involve the condensation of vanillylamine and 8-methylnonenoic acid by capsaicin synthase, the mechanism of biosynthesis is still not fully understood. In this study, deuterium labelled versions of capsaicin and the precursor vanillylamine were synthesized in order to investigate the biosynthesis of capsaicin in hot peppers.