What is the Methylprednisolone acetate?

Methylprednisolone acetate is Off-White Solid, while it's Molecular Formula is C24H32O6. Off-White Solid 6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.

What is the CAS number for Methylprednisolone acetate?

The CAS number of Methylprednisolone acetate is 53-36-1.

What is the Methylprednisolone acetate?

Methylprednisolone acetate is Off-White Solid, while it's Molecular Formula is C24H32O6. Off-White Solid 6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.

What is the CAS number for Methylprednisolone acetate?

The CAS number of Methylprednisolone acetate is 53-36-1.

Product Class

53-36-1

Product Name：Methyl Prednisolone Acetate
Molecular Formula：C₂₄H₃₂O₆
Purity：99%
Molecular Weight：416.514

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Product Details:

CasNo： 53-36-1

Molecular Formula： C₂₄H₃₂O₆

Appearance： Off-White Solid

Chinese Factory Supply Top Purity Methyl Prednisolone Acetate 53-36-1 Cheap Price

Molecular Formula:C24H32O6
Molecular Weight:416.514
Appearance/Colour:Off-White Solid
Vapor Pressure:5.41E-16mmHg at 25°C
Melting Point:206oC
Refractive Index:1.58
Boiling Point:582.5 °C at 760 mmHg
PKA:12.41±0.70(Predicted)
Flash Point:196.5 °C
PSA：100.90000
Density:1.26 g/cm³
LogP:2.37440

Methylprednisolone acetate(Cas 53-36-1) Usage

Description

Methylprednisolone acetate is the C21 acetate ester of methylprednisolone, a synthetic corticosteroid. It works by mimicking the effects of natural cortisol, a hormone produced by the adrenal glands, which helps reduce inflammation and immune response.

Uses

Methylprednisolone acetate (MPA) is classified as a synthetic glucocorticoid corticosteroid. It is primarily used as an anti-inflammatory and immunosuppressive agent. Methylprednisolone acetate works by suppressing the release of inflammatory mediators and inhibiting the immune response. It reduces inflammation by decreasing the formation, release, and activity of substances like prostaglandins and leukotrienes, which are responsible for inflammation and allergic responses.

Brand name

Depo-Medrol: One of the most widely recognized brands of methylprednisolone acetate.

Methylprednisolone acetate is typically administered through intramuscular or intra-articular injections. The effects of the injection can last from several days to weeks, depending on the condition being treated.

InChI:InChI=1/C24H32O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h5,7,10,13,16-17,19,21,27,29H,6,8-9,11-12H2,1-4H3

53-36-1 Relevant articles

Formulation and Evaluation of Pharmaceutically Equivalent Parenteral Depot Suspension of Methyl Prednisolone Acetate

A. Alam, MD., Alka Ahuja, Sanjula Baboota, S. K. Gidwani,1 and J. Ali*

, Indian J Pharm Sci. 2009 Jan-Feb; 71(1): 30–34.

For the analysis of methyl prednisolone acetate by HPTLC, pre- coated silica gel 60 F (254) plates (E. Merck India, Ltd.) were selected Formic acid, ethyl acetate, toluene, methanol, acetonitrile, diethyl ether were used separately as neat solvents. Developed chromatograms were then visualized in iodine chamber for the detection of methyl prednisolone acetate spots.

Dangers From Methylprednisolone Acetate Therapy by Intraspinal Injection

Dewey A. Nelson, MD

, Archives of neurology, 1988

Clinical trials first began in 1960 with methylprednisolone acetate (Depo-Medrol) administered intrathecally, in an attempt to treat both disk disease and multiple sclerosis. After a few reports of salubrious results, there began an out-pouring of contradictory data, which continues in 1988.

Intra-articular steroids in knee osteoarthritis: a comparative study of triamcinolone hexacetonide and methylprednisolone acetate

Debasish Pyne, Yiannakis Ioannou, Ramesh Mootoo & Asgar Bhanji

, Clinical Rheumatology, Volume 23, pages 116–120, (2004)

The aim of this study was to compare the effectiveness of triamcinolone hexacetonide (THA) and methylprednisolone acetate (MPA), given via the intra-articular route at equipotent dosage to patients with symptomatic knee OA with effusion, in a double-blind randomized comparative trial.