What is the Theophylline?

Theophylline is white to light yellow crystal powder, while it's Molecular Formula is C7H8N4O2. white to light yellow crystal powder theophylline is tonic and skin conditioning. Its cosmetic activity is not clearly or definitively established. It is most often found in anti-cellulite products. Theophylline is in the same family of bio chemicals as caffeine. It is naturally occurring in tea.

What is the CAS number for Theophylline?

The CAS number of Theophylline is 58-55-9.

What is Theophylline (58-55-9) used for?

Theophylline is a methylxanthine that acts as a weak bronchodilator. It is useful for chronic therapy and is not helpful in acute exacerbations.Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE; Ki = 100 μM). It is also a non-selective antagonist of adenosine A receptors (Ki = 14 μM for A1 and A2). Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).InChI:InChI=1/C7H10N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3-5H,1-2H3,(H,8,9)

What is the Theophylline?

Theophylline is white to light yellow crystal powder, while it's Molecular Formula is C7H8N4O2. white to light yellow crystal powder theophylline is tonic and skin conditioning. Its cosmetic activity is not clearly or definitively established. It is most often found in anti-cellulite products. Theophylline is in the same family of bio chemicals as caffeine. It is naturally occurring in tea.

What is the CAS number for Theophylline?

The CAS number of Theophylline is 58-55-9.

What is Theophylline (58-55-9) used for?

Theophylline is a methylxanthine that acts as a weak bronchodilator. It is useful for chronic therapy and is not helpful in acute exacerbations.Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE; Ki = 100 μM). It is also a non-selective antagonist of adenosine A receptors (Ki = 14 μM for A1 and A2). Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).InChI:InChI=1/C7H10N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3-5H,1-2H3,(H,8,9)

Product Class

58-55-9

Product Name：Theophylline Anhydrous
Molecular Formula：C₇H₈N₄O₂
Purity：99%
Molecular Weight：180.166

Inquiry

Product Details:

CasNo： 58-55-9

Molecular Formula： C₇H₈N₄O₂

Appearance： white to light yellow crystal powder

Factory Supply High Purity Theophylline Anhydrous 58-55-9 Low Price

Molecular Formula:C7H8N4O2
Molecular Weight:180.166
Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:2.72E-06mmHg at 25°C
Melting Point:271-273 °C
Refractive Index:1.737
Boiling Point:454.091 °C at 760 mmHg
PKA:8.77(at 25℃)
Flash Point:228.426 °C
PSA：72.68000
Density:1.466 g/cm³
LogP:-1.03970

Theophylline Anhydrous (Cas 58-55-9) Usage

Chemical Structure and Derivatives	Theophylline is a methylxanthine alkaloid and a xanthine derivative. There are more than 300 derivatives of theophylline, including aminophylline, dihydroxypropyl theophylline, oxtriphylline, and others.
Description	Theophylline Anhydrous is a xanthine derivative medication used in the treatment of respiratory diseases, particularly for chronic therapy. It acts as a weak bronchodilator, helping to alleviate symptoms associated with various lung conditions.
Chemical Properties	white to light yellow crystal powder
Uses	Theophylline Anhydrous is indicated for the management of asthma, a chronic inflammatory condition characterized by airway obstruction, inflammation, and bronchospasm. It is used to manage the reversible component of airway obstruction associated with chronic obstructive pulmonary disease (COPD).
Brand and Availability	Uniphyl (Theophylline, Anhydrous) is a bronchodilator medication previously available under the brand name Uniphyl.

InChI:InChI=1/C7H10N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3-5H,1-2H3,(H,8,9)

58-55-9 Relevant articles

Coordination polymers as potential solid forms of drugs: Three zinc(ii) coordination polymers of theophylline with biocompatible organic acids

Lou, Benyong,He, Fengdan

, p. 309 - 316 (2013)

The biocompatible organic acids such as ...

Sleep Quality and Nocturnal Respiratory Function With Once-Daily Theophylline (Uniphyl) and Inhaled Salbutamol in Patients With COPD

Godfrey C.W. Man MB, BS, FCCP a, Kenneth R. Chapman MD, FCCP b, S. Habib Ali PhD c, Andrew C. Darke PhD c

, Chest, Volume 110, Issue 3, September 1996, Pages 648-653

We conclude that, compared with salbutamol, evening administration of once-daily theophylline results in better nocturnal oxygen saturation and an improvement in the overnight change in pulmonary function, without affecting sleep architecture, in patients with COPD.

Inhibition of radical-induced DNA strand breaks by water-soluble constituents of coffee: Phenolics and caffeine metabolites

Rathod,Patel,Das,Tipparaju,Shinde,Anderson, Robert F.

, p. 480 - 487 (2013)

Epidemiological studies have associated ...

SERS multiplexing of methylxanthine drug isomersviahost-guest size matching and machine learning

Chio, Weng-I Katherine,Dinish, U. S.,Jones, Tabitha,Lee, Tung-Chun,Liu, Jia,Olivo, Malini,Parkin, Ivan P.,Perumal, Jayakumar

supporting information, p. 12624 - 12632 (2021/10/06)

Multiplexed detection and quantification...

Polymorphism in Anhydrous Theophylline—Implications on the Dissolution Rate of Theophylline Tablets

Neelima V. Phadnis, Raj Suryanarayanan

, Journal of Pharmaceutical Sciences Volume 86, Issue 11, November 1997, Pages 1256-1263

I* was prepared by dehydration of theophylline monohydrate (II). Variable temperature X-ray powder diffractometry of II revealed the following series of transitions: II → I* → I. The metastable anhydrate, I*, which has not yet been reported in the literature, appears to be related monotropically to I.

58-55-9 Process route

: 58-08-2,138455-22-8,95789-13-2
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

: 58-55-9,75448-53-2
theophylline

: 83-67-0
theobromine /

: 611-59-6
paraxanthine

: 5415-44-1
1,3,7-trimethyluric acid

Conditions

Conditions	Yield
With phosphate buffer; NADPH; recombinant rat cytochrome P₄₅₀ 1A₂; at 37 ℃; Further Variations:; Catalysts; Enzyme kinetics;
With NADPH; human cDNA-expressed cytochrome P₄₅₀ 1A₂ (supersomes); In phosphate buffer; at 37 ℃; for 60h; pH=7.4; Further Variations:; Reagents; Enzyme kinetics;

: 58-08-2,138455-22-8,95789-13-2
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

: 58-55-9,75448-53-2
theophylline

: 83-67-0
theobromine /

: 611-59-6
paraxanthine