
15664-29-6
- Product Name:Pheophorbide A
- Molecular Formula:C35H36N4O5
- Purity:99%
- Molecular Weight:592.7
Product Details:
CasNo: 15664-29-6
Molecular Formula: C35H36N4O5
Appearance: Blue to dark brown to black solid
Delivery Time: 2 weeks after order
Throughput: 100KG/Month
Purity: 99%
Synonyms: [3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo; 3-phorbinepropanoicacid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tet; [3S-(3alpha,4beta,21beta)]-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic acid; (3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid; 13-Epi-phaeophorbide-a;3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-
Boiling point: 1019.0±65.0 °C
Density: 1.282±0.06 g/cm3
Solubility: DMSO: soluble 0.5mg/mL, clear (warmed)
Stability: Light Sensitive
Uses:
Pheophorbide A is a chlorophyll-related compound studied for it's anti-tumor & anti-cancer activity.
Pheophorbide A has been used as a photosensitizer:
1.for the photodynamic therapy (PDT) in oral cancer cell lines.
2.to test its effect on inducing oxidative stress and death in L.
3.to test its effect on the viability of HeLa cells.
Biochem/physiol Actions:
Pheophorbide A, due to its photosensitizing effect, may serve as a promising bioactive compound to treat leishmaniasis. It is a metabolite of chlorophyll and possesses immunostimulation functionality. Pheophorbide-a is a photosensitizer for the photodynamic therapy. It is an ATP Binding Cassette Subfamily G Member 2 (ABCG2) transporter specific substrate. Overexpression of ATP-binding cassette (ABC) transporters in cancer cells is associated with the multidrug resistance phenotype.
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