
155030-63-0
- Product Name:Emodepside
- Molecular Formula:C60H90N6O14
- Purity:99%
- Molecular Weight:1119.39
Product Details:
CasNo: 155030-63-0
Molecular Formula: C60H90N6O14
Appearance: White to off-white Solid
Delivery Time: 2 weeks after order
Throughput: 100KG/Month
Purity: 99%
Product Name: | Emodepside |
Synonyms: | Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl;Emodepside;Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzeneprop;QHT06;PF 1022-221;Bay 44-4400;Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl];(3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone |
CAS: | 155030-63-0 |
MF: | C60H90N6O14 |
MW: | 1119.39 |
EINECS: | |
Product Categories: | API |
Mol File: | 155030-63-0.mol |
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Emodepside Chemical Properties |
Boiling point | 1219.3±65.0 °C(Predicted) |
density | 1.104±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO : ≥ 31 mg/mL (27.69 mM) |
form | Solid |
pka | 5.34±0.40(Predicted) |
color | White to off-white |
Safety Information |
Emodepside Usage And Synthesis |
Uses | Emodepside-d6 is an isotopic labeled compound of Emodepside; an anthelmintic drug very active against gastrointestinal nematodes. |
Definition | ChEBI: A cyclooctadepsipeptide consisting of D-lactoyl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, N-methyl-L-leucyl, D-lact yl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, and N-methyl-L-leucyl residues joined in sequence to give a 24-membered macrocycle. An anthelmintic, it i used with praziquantel for the treatment and control of hookworm, roundworm and tapeworm infections in cats. |
Biological Activity | Emodepside is a cyclooctadepsipeptide anthelmintic a novel mode of action involving the calcium-gated potassium channel SLO-1 in C. elegans, sometimes mediated by a latrophilin (LAT) receptor. |
Veterinary Drugs and Treatments | Emodepside/Praziquantel topical solution (Profender?) is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats. |
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