155030-63-0

  • Product Name:Emodepside
  • Molecular Formula:C60H90N6O14
  • Purity:99%
  • Molecular Weight:1119.39
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Product Details:

CasNo: 155030-63-0

Molecular Formula: C60H90N6O14

Appearance: White to off-white Solid

Delivery Time: 2 weeks after order

Throughput: 100KG/Month

Purity: 99%

Product Name: Emodepside
Synonyms: Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl;Emodepside;Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzeneprop;QHT06;PF 1022-221;Bay 44-4400;Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl];(3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone
CAS: 155030-63-0
MF: C60H90N6O14
MW: 1119.39
EINECS:  
Product Categories: API
Mol File: 155030-63-0.mol
Emodepside Structure
 
Emodepside Chemical Properties
Boiling point  1219.3±65.0 °C(Predicted)
density  1.104±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO : ≥ 31 mg/mL (27.69 mM)
form  Solid
pka 5.34±0.40(Predicted)
color  White to off-white
 
Safety Information
MSDS Information
 
 
Emodepside Usage And Synthesis
Uses Emodepside-d6 is an isotopic labeled compound of Emodepside; an anthelmintic drug very active against gastrointestinal nematodes.
Definition ChEBI: A cyclooctadepsipeptide consisting of D-lactoyl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, N-methyl-L-leucyl, D-lact yl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, and N-methyl-L-leucyl residues joined in sequence to give a 24-membered macrocycle. An anthelmintic, it i used with praziquantel for the treatment and control of hookworm, roundworm and tapeworm infections in cats.
Biological Activity Emodepside is a cyclooctadepsipeptide anthelmintic a novel mode of action involving the calcium-gated potassium channel SLO-1 in C. elegans, sometimes mediated by a latrophilin (LAT) receptor.
Veterinary Drugs and Treatments Emodepside/Praziquantel topical solution (Profender?) is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats.

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