2135-17-3
- Product Name：Flumethasone
- Molecular Formula：C22H28F2O5
- Purity：99%
- Molecular Weight：410.45
Product Details:
CasNo： 2135-17-3
Molecular Formula： C22H28F2O5
Purity： 99%
Synonyms: 6-alpha,9-alpha-difluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione;6α,9α-Difluoro-16α-methylprednisolone;6α-Fluorodexamethasone;6a-Fluoro-dexamethasone, Aniprime, Cortexilar, Flucort;Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-;6α,9α-difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione;FlumethasoneBase98.5%;(6-alpha,11-beta,16-alpha)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Melting point: 237-240°C
boiling point: 569.8±50.0 °C(Predicted)
density: 1.1621 (estimate)
solubility: acetic acid: soluble10mg/mL
form: solid
pka: 11.98±0.70(Predicted)
color: white
optical activity: [α]25/D 67.0 to 71.0°, c = 1 in dioxane
water solubility: 1mg/L(20 ºC)
uses:
A moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. Its mechanism of action is thought to inhibit arachidonic acids role in the biosynthesis of prostaglandins and leukotrienes. Flumethasone is active when it is not bound to the plasma protein transcortin. The drug flumethasone can be used to treat a variety of skin conditions, such as contact dermatitis, bug bites and eczema.
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