1369852-71-0

  • Product Name:Lotilaner
  • Molecular Formula:C20H14Cl3F6N3O3S
  • Purity:99%
  • Molecular Weight:596.76
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Product Details:

CasNo: 1369852-71-0

Molecular Formula: C20H14Cl3F6N3O3S

Purity: 99%

Synonyms: (S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylica cid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide; 2-Thiophenecarboxamide,5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-; Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor; (S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide; Lotilaner(TP-05)

Density: 1.66±0.1 g/cm3

Solubility: DMSO : ≥ 100 mg/mL (167.57 mM)

Form: Solid

Color: White to off-white

Pka: 12.52±0.46

 

Description:

lotilaner, a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
Lotilaner, like the other isooxazolines is active against fleas, mites, and ticks.  After oral administration or topical application, it can kill fleas rapidly.

 

Uses:

Lotilaner is a new member of the isoxazoline class for the treatment of flea and tick infestations in cats.

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