118864-75-8
- Product Name：(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
- Molecular Formula：C15H15N
- Purity：99%
- Molecular Weight：209.29
Product Details:
CasNo： 118864-75-8
Molecular Formula： C15H15N
Purity： 99%
Synonyms: Solifenacin Related Compound 11; (S)-1,2,3,4-four-1-phenylhydrogenisoquinoline; Solifenacin Succinate interMediate F; (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline,Solifenacin intermediate; Solifenacin Impurity A; (S)-1,2,3,4-Tetrahydro-1-phenylisoquinoline; (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
Melting point: 80-82℃
Boiling point: 338℃
Density: 1.065 g/cm3
Fp: 167℃
Solubility: Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
pka: 8.91±0.40
Form: Solid
Color: White to Off-White
Uses:
(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin intermediate.
(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease.
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