1787294-07-8
- Product Name：Remibrutinib
- Molecular Formula：C27H27F2N5O3
- Purity：99%
- Molecular Weight：507.53
Product Details:
CasNo： 1787294-07-8
Molecular Formula： C27H27F2N5O3
Purity： 99%
Synonyms: LOU064; LOU-064; N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide; Benzamide,N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-; Remibrutinib (LOU064); N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide; Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase
Boiling point: 634.8±55.0 °C
Density: 1.332±0.06 g/cm3
Solubility: DMSO: 125 mg/mL (246.29 mM)
Pka: 11.67±0.70
Form: Solid
Color: White to off-white
Storage temp.: Store at -20°C
Description:
Remibrutinib is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.
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