2389149-74-8
- Product Name：Mobocertinib succinate
- Molecular Formula：C36H45N7O8
- Purity：99%
- Molecular Weight：703.8
Product Details:
CasNo： 2389149-74-8
Molecular Formula： C36H45N7O8
Purity： 99%
Synonyms: 788Succinic acid; TAK788 succinate; TAK-788 Succinic acid; Mopotinib succinate; obocertinib Succinate (TAK-788 Succinate); Mobocertinib Succinate (TAK-788 Succinate); Mobocertinib succinate（TAK788）
Solubility: DMSO : 25 mg/mL (35.52 mM; Need ultrasonic)
Color: White to yellow
Form: Solid
Storage temp.: 4°C, sealed storage, away from moisture
Description:
Mobocertinib (TAK-788) succinate is an orally active and irreversible EGFR/HER2 inhibitor. Mobocertinib succinate potently inhibits oncogenic variants containing activating EGFRex20ins mutations with selectivity over wild-type EGFR. Mobocertinib succinate can be used in NSCLC research.
Synthesis:
Mobocertinib succinate is prepared by the reaction of Isopropyl 2-chloro-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate in the presence of an inert atmosphere.
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