682745-41-1
- Product Name:Tivozanib hydrochloride hydrate
- Molecular Formula:C22H22Cl2N4O6
- Purity:99%
- Molecular Weight:509.34
Product Details:
CasNo: 682745-41-1
Molecular Formula: C22H22Cl2N4O6
Purity: 99%
Synonyms: 1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea; N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea monohydrochloride monohydrate; Tivozanib hydrochloride; Tivozanib; Tivozanib Hydrochloride Monohydrate
Solubility: DMSO : 250 mg/mL (490.83 mM; Need ultrasonic)
Color: White to off-white
Form: Solid
storage temp.: 4°C, away from moisture and light.
Uses:
Tivozanib hydrochloride hydrate also known as AV-951 is an orally bioavailable potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively.
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