1415456-99-3

  • Product Name:Cagrilintide
  • Molecular Formula:C194H312N54O59S2
  • Purity:99%
  • Molecular Weight:4409.01
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Product Details:

CasNo: 1415456-99-3

Molecular Formula: C194H312N54O59S2

Appearance: White or off-white powder

Delivery Time: Prompt from stock

Packing: Aluminum bag

Throughput: 10KG/Month

Purity: 99%

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity[1][2][3].

In Vivo

Cagrilintide (compound 23) (0.1, 1, 3, 10, 30 nmol/kg; s.c.) reduces food intake in the rat[2].
Cagrilintide (10 nmol/kg; i.v. or s.c.) shows good pharmacokinetic parameters[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 12 weeks, 400 g Sprague Dawley male rats[2]
Dosage: 0.1, 1, 3, 10, 30 nmol/kg
Administration: S.c.; once for 80 h
Result: Reduced food intake in the rat for several days at doses in the range of 1-10 nmol/kg.
Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT05567796 Novo Nordisk A+S

Obesity

November 1, 2022 Phase 3
NCT05804162 Novo Nordisk A+S

Obesity

April 12, 2023 Phase 1
NCT05394519 Novo Nordisk A+S

Overweight|Obesity|Type 2 Diabetes Mellitus

February 1, 2023 Phase 3
NCT05669755 Novo Nordisk A+S

Obesity

March 1, 2023 Phase 3
NCT05996848 Novo Nordisk A+S

Obesity or Overweight

August 15, 2023 Phase 3
NCT04982575 Novo Nordisk A+S

Diabetes Mellitus, Type 2

August 2, 2021 Phase 2
NCT05813925 Novo Nordisk A+S

Obesity or Overweight

April 3, 2023 Phase 3
NCT04940078 Novo Nordisk A+S

Obesity & Overweight

July 7, 2021 Phase 1
NCT05564104 Novo Nordisk A+S

Hepatic Impairment

April 5, 2023 Phase 1

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