536759-91-8
- Product Name：Apixaban impurity-02
- Molecular Formula：C22H20N4O6
- Purity：99%
- Molecular Weight：436.42
Product Details:
CasNo： 536759-91-8
Molecular Formula： C22H20N4O6
Appearance： Pale Brown to Light Orange
Delivery Time： Prompt from stock
Packing： Bottle
Throughput： 10g/Month
Purity： 99%
| ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Chemical Properties |
| Melting point | 190-192°C |
| Boiling point | 658.7±55.0 °C(Predicted) |
| density | 1.40 |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | -3.80±0.20(Predicted) |
| color | Pale Brown to Light Orange |
| InChI | InChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3 |
| InChIKey | RQNAOIQEGPVYTC-UHFFFAOYSA-N |
| SMILES | C1(=O)N(C2=CC=C([N+]([O-])=O)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2 |
| LogP | 3.59 at 23℃ and pH6.57 |
| Safety Information |
| ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Usage And Synthesis |
| Uses | Ethyl 1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an intermediate in the synthesis of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation |
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