35277-02-2
- Product Name：4-Fluoro-1H-pyrazole
- Molecular Formula：C3H3FN2
- Purity：99%
- Molecular Weight：86.07
Product Details:
CasNo： 35277-02-2
Molecular Formula： C3H3FN2
Purity： 99%
Synonyms: 4-Fluoro-1H-pyrazole4-Fluoro-1H-pyrazole; 1H-Pyrazole, 4-fluoro-
Melting point: 38-40°C
Boiling point: 193℃
Density: 1.320
Fp: 70℃
Storage temp.: Keep in dark place, Sealed in dry, Room Temperature
Pka: 13.66±0.50
Form: low melting solid
Color: Colourless to off-white
InChI: InChI=1S/C3H3FN2/c4-3-1-5-6-2-3/h1-2H,(H,5,6)
InChIKey: RYXJXPHWRBWEEB-UHFFFAOYSA-N
SMILES: N1C=C(F)C=N1
Physical and chemical properties:
4-fluoro-1H-pyrazole is a yellow liquid at normal temperature and pressure. Due to its low melting point, it will show a semi-solid and semi-liquid state when the ambient temperature is high. It belongs to pyrazole derivatives and has certain alkalinity. It is soluble in strongly polar organic solvents such as N, N-dimethylformamide, etc., but 4-fluoro-1H-pyrazole is poorly soluble in low polar and non-polar organic solvents and water.
Use:
4-fluoro-1H-pyrazole is a heterocyclic organic compound and can be used as an organic intermediate.
Preparation:
4-fluoro-1H-pyrazole was prepared by hydrolyzing 2-fluoroacetate to sodium 2-fluoroacetate, then reacting with DMF to obtain (Z) -3- (dimethylamino) -2-fluoroacrolein, and finally by cyclization with dihydrohydrazine hydrochloride.
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