What is the Clotrimazole?

Clotrimazole is Crystalline, while it's Molecular Formula is C22H17ClN2. Crystalline Clotrimazole formally also is an imidazole derivative because of the presence of an imidazole ring in its structure. It is believed that, like miconazole, econazole, and other “pure”representatives of the imidazole class, it also inhibits the biosynthesis of ergosterin in thecytoplasmatic membrane of fungi.In terms of pharmacological action, clotrimazole is very similar to miconazole. It has abroad spectrum of antifungal activity. It is effective with respect to dermatophytes, and italso has an antimicrobial effect against streptococci and staphylococci. It is also effectivewith respect to trichomonases. It is very widely used, both externally and vaginally fortreating superficial infections. Synonyms of this drug are canesten, empecid, lotrimin,micosporin, and others.

What is the CAS number for Clotrimazole?

The CAS number of Clotrimazole is 23593-75-1.

What is Clotrimazole (23593-75-1) used for?

Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections. It tightly binds sterol 14-α demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane. In mammalian cells, clotrimazole potently inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 μM, respectively).InChI:InChI=1/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H

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23593-75-1

Product Name：Clotrimazole
Molecular Formula：C₂₂H₁₇ClN₂
Purity：99%
Molecular Weight：344.843

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Product Details:

CasNo： 23593-75-1

Molecular Formula： C₂₂H₁₇ClN₂

Appearance： Crystalline

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